What is a typical semaglutide dosing schedule?

For weight-management dosing (Wegovy), the FDA-approved titration is 0.25 mg weekly for 4 weeks, 0.5 mg weekly for 4 weeks, 1.0 mg weekly for 4 weeks, 1.7 mg weekly for 4 weeks, then a maintenance dose of 2.4 mg weekly. Ozempic titration is 0.25 mg, 0.5 mg, 1.0 mg, up to 2.0 mg depending on glycemic response.

How many units of semaglutide is 0.25 mg?

On a U-100 insulin syringe, 0.25 mg of semaglutide from a 2.5 mg/mL compounded vial equals 10 units (0.10 mL). From a 5 mg/mL vial it equals 5 units (0.05 mL). Always confirm your vial's concentration before dosing.

What should I do if I miss a semaglutide dose?

If it has been less than 5 days since your missed dose, take it as soon as you remember and resume your regular weekly schedule. If more than 5 days have passed, skip the missed dose and take your next dose on the regular day. Never double up.

Are Wegovy and Ozempic the same drug?

Both contain semaglutide as the active ingredient. Wegovy is FDA-approved for chronic weight management at 2.4 mg weekly. Ozempic is FDA-approved for type 2 diabetes, typically dosed up to 1.0 mg (or 2.0 mg) weekly. The medications share the same molecule but differ in approved indication and maximum dose.

Can I convert a prescription mg dose to units on an insulin syringe?

Yes, if you know the concentration of your vial (mg/mL). Units on a U-100 syringe = (mg ÷ concentration in mg/mL) × 100. Use our converter for exact math. Only applies to compounded semaglutide dispensed in vials; branded pens are pre-measured.

How long does titration take before reaching the maintenance dose?

Wegovy reaches the 2.4 mg maintenance dose at week 17 after four escalation steps of 4 weeks each. Ozempic typically reaches 1.0 mg at week 9, with optional further escalation to 2.0 mg. Slower titration is sometimes used to manage GI side effects.

What happens if I take the wrong dose?

If you take more than your prescribed dose, contact your prescriber or poison control. Common effects of excess dosing include severe nausea, vomiting, and hypoglycemia (especially if combined with insulin or sulfonylureas). Do not take an extra dose to make up for a missed one.

Is this site medical advice?

No. This site is an educational reference. All dosing information comes from FDA-approved prescribing information and peer-reviewed literature. Always consult your prescribing clinician or pharmacist about your specific regimen.

Peer-reviewed · Updated Apr 2026

Semaglutide Dosage — Quick Reference Tools

Dosage charts, unit converters, and titration schedules for Wegovy, Ozempic, and Rybelsus. Built from FDA-approved prescribing information, in plain language.

Audrey P. Baysa, RPh, MSc — medical reviewer

Reviewed by Audrey P. Baysa, RPh, MSc · Last updated April 2026

Units ↔ mg Converter

Convert between mg doses and insulin syringe units.

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Full Dosage Chart

All doses, all medications, all in one table.

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Titration Schedule

Your personalized dosing calendar.

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Missed Dose Guide

What to do if you miss a shot.

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Quick Lookup: Wegovy Standard Titration

FDA-approved escalation schedule for semaglutide (Wegovy) in chronic weight management.

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Weeks	Weekly Dose	mL (from 2.4 mg/0.75 mL pen)	Phase
1 – 4	0.25 mg	0.078 mL	Escalation 1
5 – 8	0.5 mg	0.156 mL	Escalation 2
9 – 12	1.0 mg	0.313 mL	Escalation 3
13 – 16	1.7 mg	0.531 mL	Escalation 4
17+	2.4 mg	0.75 mL	Maintenance

Source: Wegovy (semaglutide) FDA prescribing information, Novo Nordisk. Dose escalation may be slowed to manage GI side effects — consult your prescriber.

Not medical advice. This reference is educational only. Always confirm your dose with your prescribing clinician or pharmacist before injecting.

By Medication

Every branded semaglutide product has its own titration and maintenance schedule. Pick yours.

Wegovy Injection

Weight loss

Semaglutide 2.4 mg/week maintenance. 17-week titration. Subcutaneous pen.

0.25 → 0.5 → 1.0 → 1.7 → 2.4 mg

Wegovy HD (7.2 mg)

Higher dose

Escalated maintenance for patients tolerating 2.4 mg but needing more.

Maintenance: up to 7.2 mg/week

Wegovy (oral 25 mg)

Oral

Daily oral semaglutide for weight management (investigational/new indication).

3 → 7 → 14 → 25 mg daily

Ozempic

T2 diabetes

Semaglutide for glycemic control. Titrate to effect up to 2.0 mg/week.

0.25 → 0.5 → 1.0 (→ 2.0) mg

Rybelsus

Oral · Diabetes

Oral semaglutide tablet for T2 diabetes. Start 3 mg, titrate to 7 or 14 mg daily.

3 → 7 → 14 mg daily

Compounded semaglutide?

Converter

Vial concentration varies by pharmacy. Use our converter to find your units.

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Frequently Asked Questions

The most common dosing questions we get. Tap any question to expand.

Why trust Semaglutide Dosage?

①FDA labels as primary source. All dosing ranges come directly from the most recent FDA-approved prescribing information for each product.
②Pharmacist-reviewed. Every tool and page is reviewed by a licensed registered pharmacist before publication.
③No affiliate incentives. We do not sell medications, collect leads for telehealth, or take referral fees. Revenue is from clearly labeled display advertising.
④Plain language. If your patient handout uses a term, we define it. If the math is involved, we show it.

About the site Meet our reviewer

Our editorial process

Every dose on this site is sourced to the current FDA label and double-checked against Novo Nordisk's published prescribing information.
Content is drafted with a focus on clarity over hedging — but we mark off-label use explicitly where it appears.
A registered pharmacist reviews for accuracy before publication and again every 6 months.
Updates are time-stamped on the page, and significant revisions are logged in our editorial policy.